RepeatAssembler: A Package for Annotation of Full-length Repetitive
DNA Sequences in Fungal Genomes

RepeatAssembler aims to automate the identification of full-length consensus sequences for repetitive DNA fragments or the genetic material that is repeated many times throughout the genome (so-called repeats). Although there are packages with similar objectives, e.g. RECON,none fully meets the needs of researchers in comparative genomics.

Joining short repeating elements into full-length repeats is particularly intricate and handling this task properly is both the goal and the strength of our solution. RepeatAssembler analyzes as few sequences as possible to screen out all repetitive sequences. Then it builds a set of non-redundant repeats and reports the full-length consensus sequence for each element in the set.

RepeatAssembler consistently delivers repetitive sequences that agree with known full-length repeats for several fungal genomes.

(The full version of this work is presented in the Proceedings of the  Computational Systems Bioinformatics Conference SB2004, Stanford, CA, August 16-19, 2004.)

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Mark L. Farman
Department of Plant Pathology
University of Kentucky
farman@uky.edu

Joshua W. Gilkerson
Department of Computer Science
University of Kentucky
jwgilk0@cs.uky.edu

Jerzy W. Jaromczyk
Department of Computer Science
University of Kentucky
jurek@cs.uky.edu

Chuck Staben
Department of Biology
University of Kentucky
staben@uky.edu