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The organisation of synaptic function - a proteomic and informatic analysis
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Genetic and proteomic studies of the NMDA receptor complex suggest that neurotransmitter receptors are parts of larger multi-protein complexes that process the information contained in trains of electrical activity. More recent work has begun to refine this picture, combining experimental data with mathematical and computational methods. We will present a broad spectrum of data, showing how their analysis can start to reveal the organisation of synaptic function... |
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Andrew Pocklington - Biosketch
Andrew's background lies in mathematical physics, which he studied as an
undergraduate at the University of Edinburgh, and as a postgraduate at the
University of Durham. After post-doctoral research at the Yukawa Institute of
Theoretical Physics in Kyoto (Japan), and the Instituto de Fisica Teorica in Sao
Paulo (Brasil), he returned to Edinburgh to complete an MSc in Bioinformatics.
He is currently a research fellow at the University of Edinburgh, funded by the
Medical Research Council. He now applies mathematical and computational methods
to the analysis of complex biological systems, seeking to understand the
organisation of synaptic function at the molecular level. In this he works
closely with the Genes to Cognition (G2C) Program through its Principal
Scientist, Seth Grant. The G2C program brings together clinicians and basic
neuroscientists in a novel structured program that is now expanding as an
international program. This program is based on the availability of genome
sequence information and is developing new large-scale approaches to the study
of the brain.