Processing numerous sequences for a bioinformatics problem, specifically for time consuming computations substantially benefits from XGrid that harnesses Mac networks. High performance is achieved with the help from a large number of machines that execute jobs in parallel; XGrid organizes the process. We will describe our development and show scripts used for a controller (called the GridServer), agent computers (called GridAgents), and clients; three components needed in an XGrid solution. Our solution employs a network of more than 200 Mac computers, each running a A/G Blast computation. We also discuss statistics that represent speedups in processing sequences for one of our bioinformatics projects including A/T Blast and InterPro.